Elke Schaeffeler

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Pharmacogenetic Implementation Studies-Lessons Learned From the PREPARE Study.
The liver proteome of individuals with a natural UGT2B17 complete deficiency.
Innovation in cancer pharmacotherapy through integrative consideration of germline and tumor genomes.
In silico and biological analyses of missense variants of the human biliary efflux transporter ABCC2: effects of novel rare missense variants.
Metabolic activation of WHO-congeners PCB28, 52, and 101 by human CYP2A6: evidence from in vitro and in vivo experiments.
A Semi-Mechanistic Population Pharmacokinetic Model of Noscapine in Healthy Subjects Considering Hepatic First-Pass Extraction and CYP2C9 Genotypes.
Genetic associations of cardiovascular risk genes in European patients with coronary artery spasm.
Nutrimetric Validation of Solanidine as Dietary-Derived CYP2D6 Activity Marker In Vivo
Circulating Biomarkers Instead of Genotyping to Establish Metabolizer Phenotypes
A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study
Cross-ancestry GWAS defines the extended CYP2D6 locus as the principal genetic determinant of endoxifen plasma concentrations
Challenges and opportunities associated with rare-variant pharmacogenomics
Pharmacogenomics in pediatric medicine and drug development
Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation
How to manage polypharmacia?
Pharmacogenetic diagnostics to improve drug therapy in clinical practice
Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver.
α2-Adrenergic Receptor in Liver Fibrosis: Implications for the Adrenoblocker Mesedin.
Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression.
The Impact of CYP3A4*22 on Tacrolimus Pharmacokinetics and Outcome in Clinical Practice at a Single Kidney Transplant Center
A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort
Identification of Cardiomyopathy-Associated Circulating miRNA Biomarkers in Muscular Dystrophy Female Carriers Using a Complementary Cardiac Imaging and Plasma Profiling Approach
Influence of NOD2 Variants on Trichuris suis ova Treatment Outcome in Crohn’s Disease